Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745642 | 0.96 | MAOB (0.41) | MAOBMAOADRD2DRD3ALDH1A1 | |
| SCHEMBL9137631 | 0.88 | MAOB (0.41) | MAOBMAOADRD2DRD3ALDH1A1 | |
| SCHEMBL8745275 | 0.87 | MAOB (0.39) | MAOBMAOADRD2DRD3ALDH1A1 | |
| SCHEMBL9154348 | 0.87 | MAOB (0.39) | MAOBMAOADRD2DRD3ALDH1A1 | |
| SCHEMBL9154345 | 0.87 | MAOB (0.39) | MAOBMAOADRD2DRD3ALDH1A1 | |
| SCHEMBL8745218 | 0.83 | MAOB (0.35) | MAOBALDH1A1 | |
| SCHEMBL8745626 | 0.82 | TRPA1 (0.35) | MAOBMAOADRD2DRD3SIGMAR1 | |
| SCHEMBL8745257 | 0.82 | TNNC1 (0.35) | MAOBMAOAALDH1A1 | |
| SCHEMBL8745253 | 0.81 | MAOA (0.40) | MAOBMAOAHRH3 | |
| SCHEMBL8747225 | 0.81 | AR (0.32) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |