Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.48 |
| ▸ | THRA | P10827 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PCNA | P12004 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745457 | 0.88 | THRB (0.61) | THRBTHRAPPARGALDH1A1PCNA | |
| SCHEMBL3961472 | 0.85 | ALDH1A1 (0.47) | THRBTHRAPPARGALDH1A1TSHR | |
| SCHEMBL28497912 | 0.85 | ALDH1A1 (0.47) | THRBTHRAPPARGALDH1A1TSHR | |
| SCHEMBL30124119 | 0.85 | ALDH1A1 (0.47) | THRBTHRAPPARGALDH1A1TSHR | |
| SCHEMBL8745430 | 0.84 | PCNA (0.42) | THRBTHRAPCNA | |
| SCHEMBL7250996 | 0.80 | LDHA (0.59) | ALDH1A1KIF11PTGS2CYP2D6 | |
| SCHEMBL1309076 | 0.80 | LDHA (0.59) | ALDH1A1KIF11PTGS2CYP2D6 | |
| SCHEMBL1311287 | 0.80 | LDHA (0.59) | ALDH1A1KIF11PTGS2CYP2D6 | |
| SCHEMBL8745406 | 0.79 | KMT2A (0.48) | THRBTHRAPPARGALDH1A1 | |
| SCHEMBL8745433 | 0.79 | KMT2A (0.48) | THRBTHRAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612308-B1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0612308-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES. | HENNING BERLIN GMBH (DE) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009076-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH CHEMIE- UND PHARMAWERK (DE) | 1993-05-13 | — | — | WO | disclosed |