Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682315 | 0.94 | RAPGEF4 (0.42) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL8951824 | 0.94 | HSD17B10 (0.37) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL8745461 | 0.86 | ALDH1A1 (0.42) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL9811303 | 0.86 | CA2 (0.45) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL10390913 | 0.85 | NT5E (0.38) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL8008676 | 0.83 | ALDH1A1 (0.44) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL3718767 | 0.83 | CA2 (0.46) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL6937844 | 0.83 | L3MBTL1 (0.40) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL10948058 | 0.83 | HSD17B10 (0.38) | RAPGEF4HSD17B10ALDH1A1TDP1RECQL | |
| SCHEMBL6938609 | 0.81 | HSD17B10 (0.39) | HSD17B10ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015731-A | For fibers such as wool and cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |