Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30166530 | 0.90 | TSHR (0.41) | HNF4AALDH1A1FABP4CYP2D6BCAT2 | |
| SCHEMBL392931 | 0.90 | TSHR (0.41) | HNF4AALDH1A1FABP4CYP2D6BCAT2 | |
| Hydrochloric Acid SCHEMBL11760140 | 0.88 | PTGS2 (0.40) | HNF4AALDH1A1FABP4CYP2D6BCAT2 | |
| Urea SCHEMBL4970936 | 0.87 | BCAT2 (0.46) | HNF4AFABP4CYP2D6BCAT2TSHR | |
| SCHEMBL10528139 | 0.81 | HNF4A (0.54) | HNF4ACA1CA2MMP1MMP2 | |
| SCHEMBL2233205 | 0.81 | ALOX15 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| (Z)-1,2-Diphenylethene SCHEMBL28265888 | 0.81 | PTPN1 (0.44) | ALDH1A1CYP2D6LMNAMAPTSMN1; SMN2 | |
| SCHEMBL21794264 | 0.80 | TSHR (0.46) | HNF4AALDH1A1BCAT2TSHRSMN1; SMN2 | |
| SCHEMBL27690669 | 0.80 | STAT3 (0.44) | CA1CA2ALDH1A1BCAT2HSD17B10 | |
| SCHEMBL4315007 | 0.79 | ALOX15 (0.56) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655922-B1 | ANTIPROLIFERATIVE OLIGOMERS | MERRELL PHARMA INC (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5460807-A | Polyurea or polyamide oligomers useful for inhibiting smooth muscle cells | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0655922-A1 | ANTIPROLIFERATIVE OLIGOMERS. | MERRELL DOW PHARMA (US) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004164-A1 | ANTIPROLIFERATIVE OLIGOMERS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-03 | — | — | WO | disclosed |