Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 10/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745796 | 0.89 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAADORA3MEN1 | |
| SCHEMBL8745773 | 0.88 | ADORA3 (0.47) | ALDH1A1HPGDGAAADORA3MEN1 | |
| SCHEMBL8745805 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL8745804 | 0.77 | ADORA3 (0.47) | ALDH1A1HPGDGAAADORA3MEN1 | |
| SCHEMBL8745814 | 0.74 | NQO1 (0.52) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL8745781 | 0.73 | ADRA1A (0.51) | MAPK1 | |
| SCHEMBL8745791 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HPGDMEN1KMT2ARXFP1 | |
| SCHEMBL15842453 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HPGDGAAADORA3MEN1 | |
| SCHEMBL8745756 | 0.70 | KDM4E (0.64) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL28069517 | 0.70 | ADORA3 (0.55) | ALDH1A1HPGDGAAADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |