Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | HPGD | P15428 | 10/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745773 | 0.89 | ADORA3 (0.47) | ADORA3ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL8745796 | 0.88 | ALDH1A1 (0.47) | ADORA3ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL8745812 | 0.80 | ALDH1A1 (0.67) | ADORA3ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL8745795 | 0.77 | ALDH1A1 (0.46) | ADORA3ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL9148098 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL8745808 | 0.75 | DRD2 (0.52) | — | |
| SCHEMBL8745805 | 0.68 | ALDH1A1 (0.61) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL6590058 | 0.68 | ACHE (0.43) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL8807713 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL11480819 | 0.67 | HTR1A (0.48) | ALDH1A1LMNATHRBMAOBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |