Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745788 | 0.85 | ABCC1 (0.56) | CCR4BRAFADRA1DADRA1AADRA1B | |
| SCHEMBL27928276 | 0.85 | CCR4 (0.74) | CCR4BRAF | |
| SCHEMBL8745769 | 0.84 | BRAF (0.55) | ALDH1A1MAPTBRAFADRA1DADRA1A | |
| SCHEMBL8745757 | 0.83 | ABCC1 (0.54) | CCR4KDM4EALDH1A1MAPTBRAF | |
| SCHEMBL8745798 | 0.82 | BRAF (0.56) | BRAFADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL8745781 | 0.81 | ADRA1A (0.51) | ADRA1DADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL27948295 | 0.81 | CCR4 (0.63) | CCR4KDM4EALDH1A1MAPTGAA | |
| SCHEMBL8745808 | 0.80 | DRD2 (0.52) | ADRA1ADRD2HTR1A | |
| SCHEMBL8745763 | 0.80 | ADRA1A (0.55) | CCR4ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL8745809 | 0.80 | HTR2A (0.60) | CCR4KDM4EALDH1A1BRAFADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |