Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874581 | 1.00 | LMNA (0.48) | LMNAPOLBRAB9ASMN1; SMN2KEAP1 | |
| SCHEMBL877444 | 0.78 | HPGD (0.50) | LMNAPOLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9407909 | 0.71 | CA1 (0.42) | LMNAPOLBRAB9ASMN1; SMN2KEAP1 | |
| SCHEMBL876385 | 0.70 | MMP2 (0.59) | LMNAPOLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20858214 | 0.70 | EPOR (0.49) | LMNAALDH1A1KMT2A | |
| SCHEMBL7862144 | 0.68 | MMP13 (0.48) | LMNARAB9AKEAP1NFE2L2CA1 | |
| Anisole SCHEMBL28957823 | 0.68 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2CA1CA2ACHE | |
| SCHEMBL28241478 | 0.68 | SMN1; SMN2 (0.46) | LMNAPOLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22028109 | 0.68 | LTA4H (0.58) | POLBRAB9ASMN1; SMN2ACHEALDH1A1 | |
| SCHEMBL1521953 | 0.68 | LTA4H (0.58) | POLBRAB9ASMN1; SMN2ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |