Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 6/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524050 | 0.74 | ALOX5 (0.47) | KEAP1NFE2L2LMNAMAPTALDH1A1 | |
| SCHEMBL874582 | 0.71 | LMNA (0.48) | CA1CA2ACHEKEAP1NFE2L2 | |
| SCHEMBL874581 | 0.71 | LMNA (0.48) | CA1CA2ACHEKEAP1NFE2L2 | |
| SCHEMBL26023562 | 0.70 | MAPT (0.68) | LMNAMAPTALDH1A1RAB9AATM | |
| SCHEMBL305162 | 0.70 | MAPT (0.68) | LMNAMAPTALDH1A1RAB9AATM | |
| SCHEMBL19007858 | 0.69 | ALDH1A1 (0.53) | PPARALMNAALDH1A1CDC25B | |
| SCHEMBL31329294 | 0.68 | ALDH1A1 (0.61) | MAPTALDH1A1RAB9A | |
| SCHEMBL18560549 | 0.68 | CYP1A2 (0.51) | PPARALMNAALDH1A1 | |
| SCHEMBL3732372 | 0.68 | ALDH1A1 (0.59) | MMP1MMP9LMNAMAPTALDH1A1 | |
| SCHEMBL13645009 | 0.68 | KEAP1 (0.50) | CA1CA2PPARGKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |