Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365294 | 0.82 | ALDH1A1 (0.48) | MMP2MMP9MMP12METAP2METAP1 | |
| Biphenyl SCHEMBL27833272 | 0.73 | POLB (0.64) | PARP15PARP10POLBCYP3A4PARP1 | |
| Benzoic Acid SCHEMBL27504059 | 0.73 | METAP2 (0.43) | MMP2MMP9MMP12METAP2METAP1 | |
| Benzamide SCHEMBL7761457 | 0.73 | PARP1 (0.84) | PARP10POLBCYP3A4PARP1MAPT | |
| Benzamide SCHEMBL5849105 | 0.71 | POLB (0.59) | PARP15PARP10POLBCYP3A4PARP1 | |
| Benzamide SCHEMBL27802023 | 0.71 | TSHR (0.59) | PARP10POLBCYP3A4PARP1MAPT | |
| Benzamide SCHEMBL8380567 | 0.70 | L3MBTL1 (0.53) | PARP15PARP10POLBCYP3A4PARP1 | |
| Terephthalamide SCHEMBL11200537 | 0.70 | PARP10 (0.65) | PARP15PARP10POLBPARP2MEN1 | |
| SCHEMBL4794620 | 0.70 | MEN1 (0.46) | MMP2MMP9MMP12METAP2METAP1 | |
| SCHEMBL4503486 | 0.69 | MMP2 (0.50) | MMP2MMP9MMP12METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519763-B1 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO PERFUMERY CO LTD (JP) | 1997-02-05 | — | — | EP | disclosed |