Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | DBH | P09172 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162349 | 0.87 | CA2 (0.38) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL671168 | 0.79 | — | — | |
| SCHEMBL335267 | 0.78 | CA2 (0.38) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL1808224 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL2137952 | 0.77 | SELL (0.41) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL6273994 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10CA2CA1 | |
| SCHEMBL27926670 | 0.76 | TSHR (0.39) | ALDH1A1LMNAHSD17B10TDP1KDM4E | |
| SCHEMBL2183097 | 0.76 | G6PD (0.47) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL9097641 | 0.76 | IDO1 (0.46) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL1631930 | 0.76 | TRPA1 (0.50) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776354-B | Dihydroxybenzoyl hydrazone neuraminidase inhibitor as well as preparation and application thereof | 上海应用技术大学 | 2021-11-19 | — | — | CN | claimed |
| CN-109776354-A | A kind of dihydroxybenzoyl hydrazone class neuraminidase inhibitor and its preparation and application | 上海应用技术大学 | 2019-05-21 | — | — | CN | claimed |
| CN-109096450-A | Imitative mussel polymer of the hyperbranched cation of one kind and preparation method thereof | 四川汇利实业有限公司 | 2018-12-28 | — | — | CN | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| CN-102167728-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA | 2011-08-31 | — | — | CN | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| US-20110065657-A1 | Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases | PROTAMED, INC. | 2011-03-17 | — | — | US | claimed |
| JP-4370072-B2 | — | — | 2009-11-25 | — | — | JP | claimed |
| WO-2009071957-A2 | NOVEL PEPTIDES AND AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND THE USE OF THESE COMPOUNDS | BIOSTATIN GYÓGYSZERKUTATÓ-FEJLESZTÖ KFT. (HU) | 2009-06-11 | — | — | WO | claimed |
| EP-0923734-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 1999-06-23 | — | — | EP | claimed |
| US-5744465-A | Method of inhibiting a β-lactamase enzyme by administering novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1998-04-28 | — | — | US | claimed |
| WO-1998002741-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-01-22 | — | — | WO | claimed |
| US-5602118-A | A 2-((2-SUBSTITUTED ALKYL)FUR-3-YL)-THIO-),3-CARBOXY-2-CARBOPENEM DERIVATIVES; EFFECTIVE AGAINST BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA | AMERICAN CYANAMID COMPANY (US) | 1997-02-11 | — | — | US | claimed |
| EP-0617036-A2 | Novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1994-09-28 | — | — | EP | claimed |
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | claimed |
| EP-0000599-B1 | ELECTRICALLY PHOTOSENSITIVE PARTICLES FOR PHOTOELECTROPHORETIC MIGRATION IMAGING PROCESSES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-02-02 | — | — | EP | claimed |
| US-4293626-A | ORGANIC PIGMENT | EASTMAN KODAK COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| US-4272595-A | UNSATURATED NITRILE | EASTMAN KODAK COMPANY (US) | 1981-06-09 | — | — | US | claimed |
| EP-0000599-A1 | Electrically photosensitive particles for photoelectrophoretic migration imaging processes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1979-02-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065657-A1 | Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases | SNCA, PARK7, HTT | ALDH1A1 1297/4885LMNA 961/4885HPGD 1877/4885 |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | PDE4A, PDE4B, PDE4D | ALDH1A1 1228/4885LMNA 2956/4885HPGD 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.