Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.36 |
| ▸ | CA7 | P43166 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809871 | 0.77 | TRPA1 (0.50) | TRPA1ATMCYP3A4THRBCA2 | |
| SCHEMBL29451048 | 0.77 | TRPA1 (0.50) | TRPA1ATMCA2CA1ALDH1A1 | |
| SCHEMBL16954573 | 0.77 | TRPA1 (0.50) | TRPA1ATMCYP3A4THRBCA2 | |
| SCHEMBL2137032 | 0.77 | TRPA1 (0.50) | TRPA1ATMCA2CA1ALDH1A1 | |
| SCHEMBL874656 | 0.76 | ALDH1A1 (0.52) | TRPA1CYP3A4THRBCA2CA1 | |
| SCHEMBL28057552 | 0.76 | TRPA1 (0.54) | TRPA1ATMCYP3A4THRBCA2 | |
| SCHEMBL1312250 | 0.76 | CYP3A4 (0.43) | TRPA1ATMCYP3A4CA2CA1 | |
| SCHEMBL2813183 | 0.76 | TRPA1 (0.48) | TRPA1ATMCYP3A4THRBCA2 | |
| SCHEMBL671168 | 0.75 | — | — | |
| SCHEMBL335267 | 0.74 | CA2 (0.38) | TRPA1ATMCYP3A4THRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932264-B2 | Sinomenine derivatives and preparation and uses thereof | NATUREMED GROUP CORPORATION (US) | 2011-04-26 | — | — | US | claimed |
| CN-100439331-C | Intermediate of anti-AIDS medicine 'Nelfinavir' and its syntesizing process and application | SHANGHAI INST ORGANIC CHEM (CN) | 2008-12-03 | — | — | CN | claimed |
| CN-1390831-A | Intermediate of anti-AIDS medicine 'Nelfinavir' and its syntesizing process and application | SHANGHAI INST ORGANIC CHEM (CN) | 2003-01-15 | — | — | CN | claimed |
| CN-1132756-A | Antiviral ethers of aspartate protease substrate isosteres | CIBA GEIGY AG (CH) | 1996-10-09 | — | — | CN | claimed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | claimed |
| CN-102711720-A | Pigmentation preventing or improving agent | POLA CHEM IND INC | 2012-10-03 | — | — | CN | disclosed |
| CN-100439331-C | Intermediate of anti-AIDS medicine 'Nelfinavir' and its syntesizing process and application | SHANGHAI INST ORGANIC CHEM (CN) | 2008-12-03 | — | — | CN | disclosed |
| CN-100439331-C | Intermediate of anti-AIDS medicine 'Nelfinavir' and its syntesizing process and application | SHANGHAI INST ORGANIC CHEM (CN) | 2008-12-03 | — | — | CN | disclosed |
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20050215801-A1 | Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for synthesis thereof and process for preparation of the intermediates | KANEKA CORPORATION (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1553093-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-SUBSTITUTED AMINO-2,3-EPOXYPROPANES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND PROCESS FOR PREPARATION OF THE INTERMEDIATES | KANEKA CORPORATION (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-20050143317-A1 | Compounds and methods for treatment of thrombosis | EXITHERA PHARMACEUTICALS LLC | 2005-06-30 | — | — | US | disclosed |
| EP-0972760-A1 | PROCESS FOR THE PURIFICATION OR ISOLATION OF (2S, 3R)-1-HALO-2-HYDROXY-3-(PROTECTED AMINO)-4-PHENYLTHIOBUTANES OR OPTICAL ANTIPODES THEREOF | KANEKA CORPORATION (JP) | 2000-01-19 | — | — | EP | disclosed |
| EP-0969000-A1 | PROCESS FOR REDUCING $G(a)-AMINO KETONES | KANEKA CORPORATION (JP) | 2000-01-05 | — | — | EP | disclosed |
| CN-1228081-A | Process for reducing alpha-aminoketones | KANEKA CORP (JP) | 1999-09-08 | — | — | CN | disclosed |
| US-5935976-A | Antiviral ethers of aspartate protease substrate isosteres | NOVARTIS CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| US-5807891-A | RETROVIRUSES | NOVARTIS AG (CH) | 1998-09-15 | — | — | US | disclosed |
| US-5663200-A | CARBAMOYL PEPTIDE DERIVATIVES AS VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| CN-1132756-A | Antiviral ethers of aspartate protease substrate isosteres | CIBA GEIGY AG (CH) | 1996-10-09 | — | — | CN | disclosed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143317-A1 | Compounds and methods for treatment of thrombosis | SERPINC1, F11, F13B | TRPA1 4684/4885ATM 2618/4885CYP3A4 964/4885 |
| US-20050215801-A1 | Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for synthesis thereof and process for preparation of the intermediates | OXER1, RCC2, CBR3 | TRPA1 257/4885ATM 1892/4885CYP3A4 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.