Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | ADK | P55263 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3069705 | 0.97 | NISCH (0.52) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL9026316 | 0.81 | NISCH (0.50) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL13977589 | 0.81 | NISCH (0.50) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL252307 | 0.80 | NISCH (0.45) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL81650 | 0.80 | NISCH (0.59) | NISCHMTORADKALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1536214 | 0.77 | NISCH (0.56) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL28425230 | 0.77 | NISCH (0.56) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL20357190 | 0.73 | NISCH (0.39) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL28405292 | 0.73 | NISCH (0.43) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL20595289 | 0.72 | ALDH1A1 (0.43) | NISCHMTORADKALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490668-B | Pyrimidylimidazole compound, preparation method thereof and organic solderability preservative | 深圳市贝加电子材料有限公司 | 2024-04-02 | — | — | CN | claimed |
| WO-2023205507-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | ESSA PHARMA INC. (CA) | 2023-10-26 | — | — | WO | claimed |
| CN-115490668-A | Pyrimidyl imidazole compound, preparation method thereof and organic weldable protective agent | 深圳市贝加电子材料有限公司 | 2022-12-20 | — | — | CN | claimed |
| WO-2025149577-A1 | 18F-CXCR2 PET TRACER | JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBURG (DE) | 2025-07-17 | — | — | WO | disclosed |
| WO-2025133653-A1 | IMIDAZOLE DERIVATIVES AND USE THEREOF AS ANTIFIBROTIC AGENTS | VICHEM CHEMIE KUTATÓ KFT. (HU) | 2025-06-26 | — | — | WO | disclosed |
| US-20250099453-A1 | USE OF NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS FOR IMMUNOTHERAPY IN MELANOMA PATIENTS | UNIV NORTHWESTERN (US) | 2025-03-27 | — | — | US | disclosed |
| US-12083113-B2 | Use of neuronal nitric oxide synthase inhibitors for immunotherapy in melanoma patients | NORTHWESTERN UNIVERSITY (US) | 2024-09-10 | — | — | US | disclosed |
| CN-112933094-B | Methods and compositions for preventing and treating hearing loss | 听治疗有限责任公司 | 2024-07-26 | — | — | CN | disclosed |
| US-20240206208-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-06-20 | — | — | US | disclosed |
| EP-4362646-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117956822-A | Organic electroluminescent material and device | 环球展览公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-1378544-A | Substituted azoles compounds | NOVARTIS AG (CH) | 2002-11-06 | — | — | CN | disclosed |
| US-20020120139-A1 | Pyrimidinone compounds and pharmaceutical compositions containing them | HICKEY DEIRDRE MARY BERNADETTE (GB) | 2002-08-29 | — | — | US | disclosed |
| WO-2002050062-A2 | BENZIMIDAZOLE AND PYRIDYLIMIDAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | NEUROGEN CORPORATION (US) | 2002-06-27 | — | — | WO | disclosed |
| US-20020032183-A1 | Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as JNK-inhibitors | LOGRASSO PHILIP (US) | 2002-03-14 | — | — | US | disclosed |
| US-20020032183-A1 | Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as JNK-inhibitors | LOGRASSO PHILIP (US) | 2002-03-14 | — | — | US | disclosed |
| WO-2001091749-A1 | USE OF (DI-SUBSTITUTED-PHENYL)-PYRIMIDINYL-IMIDAZOLE DERIVATIVES AS JNK-INHIBITORS | MERCK & CO., INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| US-6180355-B1 | Method for diagnosing and treating chronic pelvic pain syndrome | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-01-30 | — | — | US | disclosed |
| US-5916891-A | CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |
| US-5663334-A | CYTOKINE INHIBITORS FORMED BY REACTION OF IMINE WITH SULFUR SUBSTITUTED NITRILE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120139-A1 | Pyrimidinone compounds and pharmaceutical compositions containing them | PLA2G7, PLA2G1B, PLA2G4C | NISCH 1963/4885MTOR 2468/4885ADK 863/4885 |
| US-20020032183-A1 | Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as JNK-inhibitors | MAP2, DCX, BAD | NISCH 1129/4885MTOR 373/4885ADK 1411/4885 |
| US-20250099453-A1 | USE OF NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS FOR IMMUNOTHERAPY IN MELANOMA PATIENTS | NOS2, NOS1, NOS3 | NISCH 1985/4885MTOR 926/4885ADK 1683/4885 |
| US-12083113-B2 | Use of neuronal nitric oxide synthase inhibitors for immunotherapy in melanoma patients | NOS2, NOS1, NOS3 | NISCH 1985/4885MTOR 926/4885ADK 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.