Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 10/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749248 | 0.86 | KDM2B (0.41) | ESR1KDM2BLCKMEN1CNR2 | |
| SCHEMBL8860947 | 0.82 | SLC6A3 (0.41) | PLAUESR1 | |
| SCHEMBL9043472 | 0.82 | SLC6A3 (0.41) | PLAUESR1 | |
| SCHEMBL8058782 | 0.81 | FAAH (0.43) | ESR1ESR2MEN1FAAHCNR2 | |
| SCHEMBL734321 | 0.81 | FAAH (0.43) | ESR1ESR2MEN1FAAHCNR2 | |
| SCHEMBL7598808 | 0.79 | ESR1 (0.43) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL7603629 | 0.77 | ESR1 (0.43) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL10199696 | 0.76 | ESR1 (0.38) | ESR1CYP1A2 | |
| SCHEMBL7598473 | 0.76 | KDM4E (0.46) | PLAUESR1KDM2BCYP1A2SMYD3 | |
| SCHEMBL7524110 | 0.76 | RECQL (0.43) | ESR1MEN1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416038-A4 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | — | 1992-02-26 | — | — | EP | disclosed |
| EP-0416038-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED. | TROPIX INC (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1990000164-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | disclosed |