Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749753 | 0.84 | RAB9A (0.54) | NPC1RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL3127319 | 0.84 | PDK2 (0.41) | SMN1; SMN2NPC1RAB9APDK2ALDH1A1 | |
| SCHEMBL3130536 | 0.83 | PDK2 (0.42) | SMN1; SMN2NPC1RAB9APDK2ALDH1A1 | |
| SCHEMBL11850746 | 0.81 | KMT2A (0.39) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL902241 | 0.79 | ALOX15 (0.53) | SMN1; SMN2POLBALDH1A1KDM4EHPGD | |
| SCHEMBL1444265 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL2565533 | 0.78 | KMT2A (0.40) | SMN1; SMN2POLBPDK2ALDH1A1KDM4E | |
| SCHEMBL7048126 | 0.78 | HSD11B1 (0.35) | SMN1; SMN2POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL1803317 | 0.77 | KDM4E (0.46) | SMN1; SMN2PDK2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL6613422 | 0.77 | PKM (0.43) | SMN1; SMN2POLBNPC1RAB9APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724333-B2 | Pyrazole derivative | GREEN TECH CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |
| US-20160228412-A1 | NOVEL PYRAZOLE DERIVATIVE | GREEN TECH CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-9321752-B2 | Pyrazole derivative | GREEN TECH CO., LTD. (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20150252029-A1 | Novel Pyrazole Derivative | GREEN TECH CO., LTD. (JP) | 2015-09-10 | — | — | US | disclosed |
| EP-2907805-A1 | NOVEL PYRAZOLE DERIVATIVE | Green Tech Co., Ltd. (JP) | 2015-08-19 | — | — | EP | disclosed |
| US-5663386-A | REACTION WITH AQUEOUS ALKALINE SOLUTION PRODUCES COLOR WHICH PASSES INTO AQUEOUS PHASE | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-02 | — | — | US | disclosed |
| EP-0689575-B1 | ANTHRAQUINONES AS MARKING AGENTS FOR MINERAL OILS | BASF AG (DE) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228412-A1 | NOVEL PYRAZOLE DERIVATIVE | PSEN2, PSEN1, MAPT | SMN1; SMN2 1788/4885POLB 3804/4885NPC1 206/4885 |
| US-20150252029-A1 | Novel Pyrazole Derivative | PSEN2, PSEN1, MAPT | SMN1; SMN2 1788/4885POLB 3804/4885NPC1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.