Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952503 | 0.84 | MGLL (0.48) | MGLLFAAHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8484189 | 0.81 | FAAH (0.62) | MGLLFAAHCYP1A2CYP2D6NPC1 | |
| SCHEMBL8755301 | 0.80 | RAB9A (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8755579 | 0.79 | TSHR (0.38) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL8757603 | 0.78 | EPHX1 (0.39) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9235325 | 0.78 | MGLL (0.51) | MGLLFAAHCYP1A2CYP2D6NPC1 | |
| SCHEMBL9236525 | 0.78 | MGLL (0.51) | MGLLFAAHCYP1A2CYP2D6NPC1 | |
| SCHEMBL8750598 | 0.77 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8750569 | 0.77 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8486237 | 0.77 | SMN1; SMN2 (0.52) | MGLLFAAHSMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765312-A1 | 4-CARBAMOYLOXY-PIPERIDINE-1-CARBOXYLIC ACID ESTERS: INHIBITORS OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5527804-A | 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors or cholesterol absorption | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1995034539-A1 | 4-CARBAMOYLOXY-PIPERIDINE-1-CARBOXYLIC ACID ESTERS: INHIBITORS OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-12-21 | — | — | WO | disclosed |