Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794055 | 0.86 | SCN5A (0.44) | TDP1ACHENOS3NOS1NOS2 | |
| SCHEMBL5609745 | 0.79 | ACHE (0.44) | TDP1ACHENOS3NOS1NOS2 | |
| SCHEMBL7789999 | 0.78 | HTR3E (0.43) | TDP1ACHENOS3NOS1NOS2 | |
| SCHEMBL95534 | 0.77 | ALDH1A1 (0.41) | TDP1ACHENOS3NOS1NOS2 | |
| SCHEMBL5509601 | 0.73 | NOS3 (0.41) | NOS3NOS1NOS2CYP2D6CYP2C9 | |
| SCHEMBL6746254 | 0.73 | ALDH1A1 (0.38) | TDP1ACHENOS3NOS1NOS2 | |
| SCHEMBL18245360 | 0.72 | NOS3 (0.34) | TDP1ACHENOS3NOS1NOS2 | |
| SCHEMBL7794560 | 0.72 | ALDH1A1 (0.36) | TDP1ACHEHTR3EHTR3BHTR3A | |
| P-Xylene SCHEMBL28331001 | 0.71 | ACHE (0.67) | TDP1ACHEMAPTIDO1ALDH1A1 | |
| SCHEMBL2093802 | 0.70 | NOS3 (0.34) | NOS3NOS1NOS2CYP2C9ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552925-B1 | Equilibration of cyclic siloxanes with catalysts | DOW CORNING (US) | 1997-04-09 | — | — | EP | disclosed |
| EP-0552925-A2 | Equilibration of cyclic siloxanes with novel catalysts | DOW CORNING CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5196559-A | Rearrangement to yield higher molecular weight | DOW CORNING CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4472309-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |