Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069703 | 0.84 | NAMPT (0.45) | NAMPTHDAC1PPARA | |
| SCHEMBL874757 | 0.83 | HDAC1 (0.44) | NAMPTHDAC1DGAT1KLKB1 | |
| SCHEMBL875577 | 0.82 | HDAC1 (0.43) | NAMPTHDAC1DGAT1KLKB1 | |
| SCHEMBL874398 | 0.81 | NAMPT (0.50) | NAMPTHDAC1PPARA | |
| SCHEMBL874692 | 0.80 | NAMPT (0.53) | NAMPTHDAC1PPARA | |
| SCHEMBL874730 | 0.79 | NPC1 (0.39) | PPARA | |
| SCHEMBL874763 | 0.77 | NAMPT (0.43) | NAMPTHDAC1PPARA | |
| SCHEMBL874752 | 0.75 | NAMPT (0.52) | NAMPTHDAC1PPARA | |
| SCHEMBL10069647 | 0.75 | NAMPT (0.47) | NAMPTHDAC1PPARA | |
| SCHEMBL3050217 | 0.74 | HDAC1 (0.47) | NAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |