Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.50 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.50 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.50 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.50 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.50 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.50 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.50 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.50 |
| ▸ | CACNA1E | Q15878 | 3/20 | 0.50 |
| ▸ | CACNA2D4 | Q7Z3S7 | 3/20 | 0.50 |
| ▸ | CACNA2D3 | Q8IZS8 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753094 | 0.85 | HTR6 (0.69) | HTR6KDRCYP19A1YES1JAK3 | |
| SCHEMBL10466866 | 0.85 | PLA2G4A (0.44) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| Hydrochloric Acid SCHEMBL8986547 | 0.84 | HTR6 (0.67) | HTR6KDRCYP19A1YES1JAK3 | |
| SCHEMBL7682159 | 0.84 | HTR6 (0.46) | HTR6KDREGFRIGF1RFLT4 | |
| SCHEMBL8233006 | 0.81 | HTR6 (0.48) | HTR6KDREGFRIGF1RFLT4 | |
| SCHEMBL8986536 | 0.80 | TAAR1 (0.50) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL13621791 | 0.78 | ALDH1A1 (0.66) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL20769719 | 0.77 | ALDH1A1 (0.65) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL379053 | 0.77 | ADRB2 (0.64) | HTR6HTR2ATRPM8 | |
| SCHEMBL29043456 | 0.76 | PLA2G2A (0.69) | HTR6KDREGFRIGF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623138-B1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNION PHARMA SCIENT APPL (FR) | 1997-05-21 | — | — | EP | disclosed |
| US-5480983-A | ANALGESICS, HYPOTENSIVE AGENTS | LABORATOIRES UPSA (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0623138-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNION PHARMA SCIENT APPL (FR) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014102-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRES UPSA (FR) | 1993-07-22 | — | — | WO | disclosed |