Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.43 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.43 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494723 | 0.91 | PLA2G4A (0.55) | PLA2G4AHTR6KDREGFRIGF1R | |
| SCHEMBL10465300 | 0.86 | EGFR (0.57) | HTR6KDREGFRIGF1RFLT4 | |
| SCHEMBL8758708 | 0.85 | HTR6 (0.51) | PLA2G4AHTR6CACNB4CACNA1ACACNA1G | |
| SCHEMBL10494798 | 0.84 | HTR6 (0.41) | PLA2G4AHTR6KDREGFRIGF1R | |
| SCHEMBL10465308 | 0.84 | CACNB4 (0.42) | PLA2G4AHTR6CACNB4CACNA1ACACNA1G | |
| SCHEMBL9597127 | 0.82 | HTR6 (0.35) | PLA2G4AHTR6KDREGFRIGF1R | |
| SCHEMBL9800395 | 0.80 | PLA2G4A (0.60) | PLA2G4AHTR6KDREGFRIGF1R | |
| SCHEMBL10494701 | 0.80 | EGFR (0.48) | PLA2G4AHTR6KDREGFRIGF1R | |
| SCHEMBL5918471 | 0.79 | ADRB2 (0.56) | HTR6 | |
| Hydrochloric Acid SCHEMBL7558473 | 0.78 | ADRB2 (0.54) | HTR6KDREGFRIGF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894387-A | RELIEF FROM PAIN FROM VASODILATION | GLAXO GROUP LIMITED (GB) | 1990-01-16 | — | — | US | disclosed |
| EP-0147107-B1 | INDOLE DERIVATES | GLAXO GROUP LIMITED (GB) | 1989-08-02 | — | — | EP | disclosed |
| EP-0147107-A1 | Indole derivates | GLAXO GROUP LIMITED (GB) | 1985-07-03 | — | — | EP | disclosed |