Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.33 |
| ▸ | HPGD | P15428 | 9/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759384 | 0.84 | TSHR (0.35) | ALDH1A1SMN1; SMN2TDP1L3MBTL1MAOB | |
| SCHEMBL8760945 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL8760430 | 0.76 | CYP1A2 (0.41) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9799431 | 0.71 | NQO1 (0.41) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9654087 | 0.68 | NQO1 (0.48) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9618130 | 0.68 | NQO1 (0.48) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6779563 | 0.67 | LTA4H (0.51) | MAPTKMT2AGAALMNAFFAR1 | |
| SCHEMBL11967122 | 0.65 | TSHR (0.45) | ALDH1A1L3MBTL1MAOBGAAAR | |
| SCHEMBL30522129 | 0.65 | FFAR1 (0.49) | RXFP1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL20157368 | 0.65 | TAAR1 (0.47) | MAPTSMN1; SMN2NPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543238-B1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5256666-A | Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0543238-A1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF Aktiengesellschaft (DE) | 1993-05-26 | — | — | EP | disclosed |