Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654087 | 0.76 | NQO1 (0.48) | NQO1NR1H2NR1H3TSHRTDP1 | |
| SCHEMBL9618130 | 0.76 | NQO1 (0.48) | NQO1NR1H2NR1H3TSHRTDP1 | |
| SCHEMBL9514185 | 0.75 | P2RX7 (0.39) | NQO1KDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8538312 | 0.72 | FDFT1 (0.43) | TDP1KDM4ESMN1; SMN2LTA4HL3MBTL1 | |
| SCHEMBL9804553 | 0.71 | NQO1 (0.39) | NQO1TSHRTDP1KDM4EALDH1A1 | |
| Silafluofen SCHEMBL27295 | 0.71 | LTA4H (0.43) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8760946 | 0.71 | RXFP1 (0.38) | NQO1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8760945 | 0.71 | ALDH1A1 (0.34) | NQO1KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6779563 | 0.70 | LTA4H (0.51) | LMNALTA4HMAPT | |
| SCHEMBL9559840 | 0.69 | NQO1 (0.56) | NQO1TSHRTDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0224024-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |