Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759951 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MTNR1ALMNAMAPTKMT2A | |
| SCHEMBL8760946 | 0.79 | RXFP1 (0.38) | ALDH1A1NQO1GAANPC1RAB9A | |
| SCHEMBL8760430 | 0.76 | CYP1A2 (0.41) | ALDH1A1NQO1MTNR1AGAANPC1 | |
| SCHEMBL28323985 | 0.72 | LIPG (0.40) | ALDH1A1LMNAMAPTKDM4EKMT2A | |
| SCHEMBL9799431 | 0.71 | NQO1 (0.41) | ALDH1A1NQO1NPC1RAB9ALMNA | |
| SCHEMBL8981378 | 0.69 | ALDH1A1 (0.42) | ALDH1A1ERN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2947217 | 0.69 | ALDH1A1 (0.37) | ALDH1A1ERN1NPC1RAB9ALMNA | |
| SCHEMBL9618130 | 0.68 | NQO1 (0.48) | ALDH1A1NQO1NPC1RAB9AMAPT | |
| SCHEMBL9654087 | 0.68 | NQO1 (0.48) | ALDH1A1NQO1NPC1RAB9AMAPT | |
| SCHEMBL548566 | 0.67 | ALDH1A1 (0.46) | ALDH1A1ERN1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543238-B1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5256666-A | Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0543238-A1 | 3-Isoxazolylphenyl-compounds, their preparation and application | BASF Aktiengesellschaft (DE) | 1993-05-26 | — | — | EP | disclosed |