Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 11/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764456 | 0.91 | TRPA1 (0.36) | RIPK1ALDH1A1HSD11B1 | |
| SCHEMBL8763886 | 0.85 | P2RX7 (0.37) | RIPK1 | |
| SCHEMBL8764701 | 0.84 | HSD11B1 (0.37) | HTTHSD11B1 | |
| SCHEMBL8763626 | 0.83 | GRM2 (0.36) | RIPK1HSD11B1 | |
| SCHEMBL8763834 | 0.82 | — | — | |
| SCHEMBL8763796 | 0.82 | GRM2 (0.35) | — | |
| SCHEMBL8762717 | 0.81 | GRM2 (0.44) | ALDH1A1 | |
| SCHEMBL8762591 | 0.78 | HSD11B1 (0.37) | HTTALDH1A1CYP3A4HSD11B1RAB9A | |
| SCHEMBL8764380 | 0.77 | TSHR (0.41) | ALDH1A1HSD11B1 | |
| SCHEMBL8763981 | 0.76 | P2RX7 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |