Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764456 | 0.85 | TRPA1 (0.36) | P2RX7RIPK1 | |
| SCHEMBL8762997 | 0.85 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL8762976 | 0.84 | ALDH1A1 (0.33) | RIPK1 | |
| SCHEMBL8764321 | 0.82 | GRM2 (0.35) | RIPK1 | |
| SCHEMBL8763852 | 0.81 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL8764701 | 0.81 | HSD11B1 (0.37) | — | |
| SCHEMBL8763796 | 0.81 | GRM2 (0.35) | — | |
| SCHEMBL8762717 | 0.80 | GRM2 (0.44) | P2RX7 | |
| SCHEMBL8762591 | 0.79 | HSD11B1 (0.37) | P2RX7 | |
| SCHEMBL8763834 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |