SCHEMBL8765273

SCHEMBL8765273

CN(C(=O)OC(C)(C)C)[C@@H](Cc1ccc(OCC(=O)O)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
ITGB3 P05106 2/20 0.45
ITGA2B P08514 2/20 0.45
MMP13 P45452 1/20 0.41
EPHX2 P34913 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HDAC8 Q9BY41 1/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
PTPN7 P35236 1/20 0.39
KMT2A Q03164 1/20 0.39
PTPN12 Q05209 1/20 0.39
ALOX15 P16050 1/20 0.39
MAOB P27338 1/20 0.39
PTPN1 P18031 1/20 0.38
PPARG P37231 1/20 0.38
LDHA P00338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10785304 0.86 MMP13 (0.43) ITGB3ITGA2BMMP13ALDH1A1MEN1
SCHEMBL3776724 0.86 LDHA (0.54) ITGB3ITGA2BMMP13MEN1KMT2A
SCHEMBL6942693 0.86 LDHA (0.54) ITGB3ITGA2BMMP13MEN1KMT2A
SCHEMBL6474783 0.86 ITGB3 (0.55) ITGB3ITGA2BMAOBPTPN1PPARG
SCHEMBL16634946 0.86 ITGB3 (0.55) ITGB3ITGA2BMAOBPTPN1PPARG
SCHEMBL29397771 0.86 ITGB3 (0.55) ITGB3ITGA2BMAOBPTPN1PPARG
SCHEMBL8765621 0.85 ITGB3 (0.54) ITGB3ITGA2BMMP13MAOBPTPN1
SCHEMBL2292028 0.84 MMP13 (0.57) ITGB3ITGA2BMMP13MEN1KMT2A
SCHEMBL27166300 0.84 ITGB3 (0.46) ITGB3ITGA2BMMP13PPARG
SCHEMBL25173080 0.83 PPARG (0.40) ITGB3ITGA2BMMP13PPARGLDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624599-B1 Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications OREAL (FR) 1997-07-30 EP claimed