Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942693 | 1.00 | LDHA (0.54) | LDHAPPARGPPARAL3MBTL1MMP13 | |
| SCHEMBL10785304 | 0.90 | MMP13 (0.43) | LDHAPPARGPPARAMMP13ITGB3 | |
| SCHEMBL3777215 | 0.88 | LDHA (0.46) | LDHAL3MBTL1MMP13 | |
| SCHEMBL31407616 | 0.88 | LDHA (0.46) | LDHAPPARGPPARAL3MBTL1MMP13 | |
| SCHEMBL3638571 | 0.88 | LDHA (0.46) | LDHAPPARGPPARAL3MBTL1MMP13 | |
| SCHEMBL2292028 | 0.87 | MMP13 (0.57) | PPARGPPARAMMP13ITGB3ITGA2B | |
| SCHEMBL31278485 | 0.87 | EPHX2 (0.46) | LDHAITGB3ITGA2B | |
| SCHEMBL25173080 | 0.86 | PPARG (0.40) | LDHAPPARGPPARAMMP13ITGB3 | |
| SCHEMBL6661008 | 0.86 | CTSS (0.44) | MMP13ITGB3ITGA2BREN | |
| SCHEMBL4778626 | 0.86 | CTSS (0.44) | MMP13ITGB3ITGA2BREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727552-A2 | PASSIVE PERMEABLE PCSK9 ANTAGONIST COMPOUNDS | Merck Sharp & Dohme LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PEPTIDREAM INC (JP) | 2026-01-15 | — | — | US | disclosed |
| EP-4534524-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | PeptiDream Inc. (JP) | 2025-04-09 | — | — | EP | disclosed |
| WO-2024259310-A2 | PASSIVE PERMEABLE PCSK9 ANTAGONIST COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2024-12-19 | — | — | WO | disclosed |
| US-20100317697-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-12-16 | — | — | US | disclosed |
| US-20100317697-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-12-16 | — | — | US | disclosed |
| WO-2009096996-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-06 | — | — | WO | disclosed |
| EP-0956033-B1 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | UNIV ILLINOIS (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6380156-B1 | HAVING ANTIVIRAL, ANTITUMOR, AND IMMUNOSUPPRESSIVE ACTIVITIES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOIS | 2002-04-30 | — | — | US | disclosed |
| EP-0589949-B1 | NEW PEPTIDES (DIDEMNINS), THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| US-5504189-A | HEXAPEPTIDES; ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| WO-1993000362-A1 | NEW PEPTIDES (DIDEMNINS), THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015313-A1 | AMINO ACID ACTIVE ESTER AND SALT THEREOF | NSUN3, BCAT1, SLC43A1 | LDHA 1324/4885PPARG 3131/4885PPARA 2794/4885 |
| US-20100317697-A1 | Renin Inhibitors | REN, ACE, SERPINB1 | LDHA 843/4885PPARG 3070/4885PPARA 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.