Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520354 | 0.96 | MMP13 (0.54) | MMP13NPY5RPPARGPPARAITGB3 | |
| SCHEMBL28520356 | 0.96 | MMP13 (0.54) | MMP13NPY5RPPARGPPARAITGB3 | |
| SCHEMBL2476924 | 0.90 | MMP13 (0.46) | MMP13ITGB3ITGA2B | |
| SCHEMBL1401042 | 0.90 | MMP13 (0.46) | MMP13ITGB3ITGA2B | |
| SCHEMBL65502 | 0.90 | MMP13 (0.46) | MMP13ITGB3ITGA2B | |
| SCHEMBL18248052 | 0.87 | ALDH1A1 (0.48) | MMP13PPARGPPARAITGB3ITGA2B | |
| SCHEMBL1401223 | 0.87 | ALDH1A1 (0.48) | MMP13PPARGPPARAITGB3ITGA2B | |
| SCHEMBL10785304 | 0.87 | MMP13 (0.43) | MMP13PPARGPPARAITGB3ITGA2B | |
| SCHEMBL3776724 | 0.87 | LDHA (0.54) | MMP13PPARGPPARAITGB3ITGA2B | |
| SCHEMBL6942693 | 0.87 | LDHA (0.54) | MMP13PPARGPPARAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989480-B2 | Aryl amino acid derivatives as inhibitors for treating inflammation | DECODE GENETICS EHF (IS) | 2011-08-02 | — | — | US | disclosed |
| US-20080033024-A1 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF. (IS) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033024-A1 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS FOR TREATING INFLAMMATION | LTA4H, LTB4R2, LTB4R | MMP13 1066/4885NPY5R 1165/4885PPARG 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.