Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474783 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BMAOBPTPN1LTA4H | |
| SCHEMBL16634946 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BMAOBPTPN1LTA4H | |
| SCHEMBL29397771 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BMAOBPTPN1LTA4H | |
| SCHEMBL18918265 | 0.85 | LTA4H (0.52) | ITGB3ITGA2BMAOBLTA4HLAP3 | |
| SCHEMBL8765273 | 0.85 | SMN1; SMN2 (0.46) | ITGB3ITGA2BMAOBPTPN1PPARG | |
| SCHEMBL1401042 | 0.83 | MMP13 (0.46) | ITGB3ITGA2BMMP13REN | |
| SCHEMBL65502 | 0.83 | MMP13 (0.46) | ITGB3ITGA2BMMP13REN | |
| SCHEMBL2476924 | 0.83 | MMP13 (0.46) | ITGB3ITGA2BMMP13REN | |
| SCHEMBL17923777 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BMAOBPPARGPPARA | |
| SCHEMBL2292028 | 0.81 | MMP13 (0.57) | ITGB3ITGA2BPPARGPPARAMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624599-B1 | Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |