Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651909 | 0.85 | TAAR1 (0.44) | OGG1TAAR1RXRARXRBMEN1 | |
| SCHEMBL1808381 | 0.83 | RXRA (0.50) | RXRARXRBMEN1KMT2AGAA | |
| SCHEMBL11579352 | 0.78 | ACHE (0.54) | MEN1KMT2APARP1GAAALDH1A1 | |
| SCHEMBL11578736 | 0.78 | TAAR1 (0.56) | TAAR1PARP1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9987172 | 0.77 | GPBAR1 (0.46) | MTNR1AMTNR1BGAATSHRALDH1A1 | |
| SCHEMBL1807403 | 0.77 | GPBAR1 (0.46) | MTNR1AMTNR1BGAATSHRALDH1A1 | |
| SCHEMBL23067916 | 0.76 | HPGD (0.49) | MEN1KMT2APARP1HPGDACHE | |
| SCHEMBL8059974 | 0.76 | OGG1 (0.58) | OGG1KMT2AALDH1A1KDM4E | |
| SCHEMBL11582759 | 0.76 | HSD17B10 (0.44) | KMT2APARP1GAAALDH1A1KDM4E | |
| SCHEMBL8765732 | 0.76 | CYP3A4 (0.53) | PARP1ALDH1A1CA2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |