Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223161 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MMP2MMP7MMP14FFAR1 | |
| SCHEMBL8765346 | 0.84 | ALDH1A1 (0.74) | CA2SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL8765878 | 0.82 | MMP2 (0.47) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL7946206 | 0.80 | FLT1 (0.44) | CA2SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL28669640 | 0.80 | CA12 (0.56) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL3386873 | 0.76 | FLT1 (0.50) | CA2SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL31531993 | 0.76 | FLT1 (0.50) | CA2SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL1755241 | 0.75 | PTGDR2 (0.46) | CA2SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL3671530 | 0.74 | NPC1 (0.69) | ALDH1A1MMP2MMP7MMP14 | |
| SCHEMBL924405 | 0.74 | ALDH1A1 (0.69) | CA2CA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |