Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765315 | 0.84 | ALDH1A1 (0.59) | PTGDR2ALDH1A1LMNA | |
| SCHEMBL11223161 | 0.83 | ALDH1A1 (0.57) | MMP2MMP7MMP14PTGDR2FFAR1 | |
| SCHEMBL7948250 | 0.83 | GAA (0.44) | PTGDR2ALDH1A1CA12CA1CA2 | |
| SCHEMBL8765860 | 0.82 | CA2 (0.54) | MMP2MMP7MMP14FFAR1ALDH1A1 | |
| SCHEMBL16888036 | 0.81 | PTGDR2 (0.53) | PTGDR2ALDH1A1 | |
| SCHEMBL28669640 | 0.79 | CA12 (0.56) | MMP2MMP7MMP14FFAR1ALDH1A1 | |
| SCHEMBL7946185 | 0.75 | VCAM1 (0.38) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7946495 | 0.75 | LMNA (0.49) | PTGDR2ALDH1A1LMNA | |
| SCHEMBL8765311 | 0.75 | CA12 (0.43) | MMP2PTGDR2CA12CA1CA2 | |
| SCHEMBL23049594 | 0.74 | MMP2 (0.59) | MMP2MMP7MMP14FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |