Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601374 | 0.83 | MAPK1 (0.48) | GAAPSIP1PTGDR2ALDH1A1MAPT | |
| SCHEMBL1755241 | 0.82 | PTGDR2 (0.46) | FLT1FLT4KDRPTGS2SMN1; SMN2 | |
| SCHEMBL5936707 | 0.81 | LMNA (0.50) | FLT1FLT4KDRPTGS2SMN1; SMN2 | |
| SCHEMBL8765860 | 0.80 | CA2 (0.54) | FLT1FLT4KDRSMN1; SMN2CA2 | |
| SCHEMBL7948250 | 0.80 | GAA (0.44) | GAAPSIP1CA2PTGDR2ALDH1A1 | |
| SCHEMBL31531993 | 0.79 | FLT1 (0.50) | FLT1FLT4KDRPTGS2SMN1; SMN2 | |
| SCHEMBL863161 | 0.79 | PTGS2 (0.58) | FLT1FLT4KDRPTGS2CA2 | |
| SCHEMBL3386873 | 0.79 | FLT1 (0.50) | FLT1FLT4KDRPTGS2SMN1; SMN2 | |
| SCHEMBL242381 | 0.79 | FLT1 (0.46) | FLT1FLT4KDRPTGS2CA2 | |
| SCHEMBL29296542 | 0.79 | GAA (0.43) | FLT1FLT4KDRPTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773616-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| US-20150259352-A1 | Chemical Compounds | PFIZER LTD (GB) | 2015-09-17 | — | — | US | disclosed |
| US-20150105396-A1 | Chemical Compounds | PFIZER LTD (GB) | 2015-04-16 | — | — | US | disclosed |
| US-8952008-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2015-02-10 | — | — | US | disclosed |
| US-20140171435-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2014-06-19 | — | — | US | disclosed |
| US-6258984-B1 | CHLORINATION OF P-ALKYLBENZENESULFONYL CHLORIDE | CLARIANT GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0571405-B1 | Process for preparing 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and intermediates | HOECHST AG (DE) | 1996-05-01 | — | — | EP | disclosed |
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |
| EP-0500639-B1 | PROCESS FOR THE PRODUCTION OF ALKYL-(3-CHLOROPHENYL) SULPHONES | HOECHST AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| EP-0571405-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE. | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-5241120-A | PROCESS FOR THE PREPARATION OF ALKYL 3-CHLOROPHENYL SULFONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| WO-1992014700-A1 | PROCESS FOR PREPARING 4-ALKYLSULFONYL-1-ALKYL-2-CHLOROBENZENES AND THE LIKE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | disclosed |
| EP-0500639-A1 | PROCESS FOR THE PRODUCTION OF ALKYL-(3-CHLOROPHENYL) SULPHONES. | HOECHST AG (DE) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991007384-A1 | PROCESS FOR THE PRODUCTION OF ALKYL-(3-CHLOROPHENYL) SULPHONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259352-A1 | Chemical Compounds | GABRA5, GABRA4, GABRA3 | FLT1 2098/4885FLT4 1412/4885KDR 1155/4885 |
| US-20150105396-A1 | Chemical Compounds | GABRA5, GABRA4, GABRA3 | FLT1 2098/4885FLT4 1412/4885KDR 1155/4885 |
| US-20140171435-A1 | Chemical Compounds | GABRA5, GABRA4, GABRA3 | FLT1 2098/4885FLT4 1412/4885KDR 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.