SCHEMBL8766121

SCHEMBL8766121

CCCc1ccccc1N1C(=O)C(Cl)=C(Cl)C1=O

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 6/20 0.56
NR1H3 Q13133 6/20 0.56
PKM P14618 1/20 0.52
MGLL Q99685 1/20 0.49
TSHR P16473 1/20 0.44
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM5A P29375 1/20 0.40
BCL2A1 Q16548 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30302472 0.79 MGLL (0.79) NR1H2NR1H3PKMMGLLTSHR
SCHEMBL3774325 0.79 MGLL (0.79) NR1H2NR1H3PKMMGLLTSHR
SCHEMBL8766123 0.76 KDM5A (0.49) NR1H2NR1H3PKMMGLLTSHR
SCHEMBL8765659 0.76 PKM (0.49) NR1H2NR1H3PKMMGLLTSHR
SCHEMBL29378620 0.72 NR1H3 (1.00) NR1H2NR1H3MGLL
SCHEMBL27586782 0.72 NR1H3 (0.70) NR1H2NR1H3PKMMGLLTSHR
SCHEMBL11211240 0.71 MGLL (0.63) PKMMGLLTSHRMEN1MAPT
SCHEMBL2184085 0.71 CRHBP (0.56) PKMMGLLLMNAMAPT
SCHEMBL10018469 0.69 NR1H3 (0.68) NR1H2NR1H3MGLLTSHRLMNA
SCHEMBL7560021 0.69 PKM (0.43) NR1H2NR1H3PKMMGLLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0425709-B1 UNDERSEA ANTIFOULING AGENT NIPPON OILS & FATS CO LTD (JP) 1997-08-13 EP claimed
US-5229436-A 2-(thiocyanomethylthio)benzothiazole, N-(dialkylphenyl)-dichloromaleimide, film former, and dialkylpolysulfide; ropes NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-07-20 US claimed
EP-0425709-A1 UNDERSEA ANTIFOULING AGENT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-05-08 EP claimed
EP-0425709-B1 UNDERSEA ANTIFOULING AGENT NIPPON OILS & FATS CO LTD (JP) 1997-08-13 EP disclosed
US-5290834-A Method for controlling elution rate of agent ROHM & HAAS COMPANY (US) 1994-03-01 US disclosed
US-5229436-A 2-(thiocyanomethylthio)benzothiazole, N-(dialkylphenyl)-dichloromaleimide, film former, and dialkylpolysulfide; ropes NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-07-20 US disclosed
EP-0425709-A1 UNDERSEA ANTIFOULING AGENT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-05-08 EP disclosed
EP-0425709-A1 UNDERSEA ANTIFOULING AGENT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-05-08 EP disclosed
WO-1990014011-A1 UNDERSEA ANTIFOULING AGENT NIPPON OIL AND FATS CO., LTD. (JP) 1990-11-29 WO disclosed