Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801601 | 0.77 | ALDH1A1 (0.61) | L3MBTL1SMN1; SMN2MEN1KMT2AHRH3 | |
| SCHEMBL11432095 | 0.76 | GAA (0.68) | L3MBTL1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7389188 | 0.76 | L3MBTL1 (0.73) | L3MBTL1MEN1KMT2AHRH3RAB9A | |
| SCHEMBL8767909 | 0.75 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2HRH3LMNAACACB | |
| SCHEMBL8766644 | 0.74 | HAO1 (0.43) | SMN1; SMN2ATMKDM4EMEN1KMT2A | |
| SCHEMBL3084212 | 0.74 | ALDH1A1 (0.53) | L3MBTL1SMN1; SMN2ATMKDM4EMEN1 | |
| SCHEMBL11200681 | 0.74 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2KMT2AHRH3MAPK1 | |
| SCHEMBL13534477 | 0.70 | L3MBTL1 (0.70) | L3MBTL1SMN1; SMN2MEN1KMT2AHRH3 | |
| SCHEMBL12947867 | 0.70 | L3MBTL1 (0.70) | L3MBTL1SMN1; SMN2MEN1KMT2AHRH3 | |
| SCHEMBL13215733 | 0.70 | L3MBTL1 (0.65) | L3MBTL1SMN1; SMN2KMT2AHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | claimed |