Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15972059 | 0.80 | ALDH1A1 (0.42) | PRMT5WDR77LMNACCR2PTGS2 | |
| SCHEMBL28801601 | 0.75 | ALDH1A1 (0.61) | L3MBTL1HRH3POLBLMNASMN1; SMN2 | |
| SCHEMBL8766483 | 0.75 | GSR (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL8766562 | 0.75 | L3MBTL1 (0.50) | L3MBTL1HRH3POLBLMNASMN1; SMN2 | |
| SCHEMBL11432095 | 0.75 | GAA (0.68) | L3MBTL1POLBSMN1; SMN2ACACB | |
| SCHEMBL7389188 | 0.74 | L3MBTL1 (0.73) | L3MBTL1HRH3POLB | |
| SCHEMBL3919431 | 0.74 | L3MBTL1 (0.54) | L3MBTL1HRH3CA12CA1CA2 | |
| SCHEMBL3369476 | 0.73 | PTGDR2 (0.42) | PRMT5WDR77POLBPTGS2KCNH2 | |
| SCHEMBL8236801 | 0.72 | HRH3 (0.64) | HRH3LMNACCR2 | |
| SCHEMBL11200681 | 0.72 | L3MBTL1 (0.76) | L3MBTL1HRH3SMN1; SMN2ACACBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |