Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766483 | 0.78 | GSR (0.47) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL8766644 | 0.77 | HAO1 (0.43) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL24634980 | 0.72 | PKM (0.56) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL31185587 | 0.71 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL1535161 | 0.70 | GSK3B (0.57) | — | |
| SCHEMBL10830356 | 0.70 | GSK3B (0.53) | RAB9ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL5739984 | 0.69 | RAB9A (0.69) | RAB9ASMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL5739537 | 0.69 | RAB9A (0.69) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL5738542 | 0.69 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL9700347 | 0.68 | RAB9A (0.39) | RAB9ASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |