Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772464 | 0.84 | KMT2A (0.45) | ADRA1BMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL8766682 | 0.76 | MEN1 (0.46) | ADRA1BMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL8766432 | 0.76 | HTT (0.40) | ADRA1BMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL10875798 | 0.74 | ADRA1B (0.61) | ADRA1BMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7083850 | 0.69 | PKM (0.39) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8767658 | 0.69 | NPC1 (0.44) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL24937825 | 0.66 | PIK3CD (0.50) | ADRA1BMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11249992 | 0.66 | POLB (0.38) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL11513541 | 0.65 | NPC1 (0.58) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL8767339 | 0.65 | HTT (0.38) | ADRA1BMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | claimed |