Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766491 | 0.79 | KDM4E (0.41) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL11513541 | 0.74 | NPC1 (0.58) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL4314794 | 0.71 | PKM (0.44) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL4317705 | 0.71 | PKM (0.44) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL8766975 | 0.69 | ADRA1B (0.44) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL8766682 | 0.68 | MEN1 (0.46) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL8767631 | 0.67 | LMNA (0.40) | NPC1RAB9ATDP1 | |
| SCHEMBL2132367 | 0.66 | L3MBTL1 (0.60) | NPC1RAB9AKMT2AL3MBTL1MEN1 | |
| SCHEMBL8766870 | 0.65 | TRPA1 (0.42) | — | |
| SCHEMBL917005 | 0.65 | L3MBTL1 (0.68) | NPC1RAB9AKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | claimed |