Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766975 | 0.76 | ADRA1B (0.44) | MEN1KMT2ANPC1RAB9AADRA1B | |
| SCHEMBL8767658 | 0.68 | NPC1 (0.44) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL8766432 | 0.67 | HTT (0.40) | MEN1KMT2ANPC1RAB9AADRA1B | |
| SCHEMBL8772464 | 0.67 | KMT2A (0.45) | MEN1KMT2ANPC1RAB9AADRA1B | |
| SCHEMBL4314794 | 0.66 | PKM (0.44) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL4317705 | 0.66 | PKM (0.44) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL10875798 | 0.64 | ADRA1B (0.61) | MEN1KMT2ANPC1RAB9AADRA1B | |
| SCHEMBL25015762 | 0.63 | ADRA1B (0.53) | MEN1KMT2AADRA1BL3MBTL1 | |
| SCHEMBL7083850 | 0.63 | PKM (0.39) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8772367 | 0.63 | LMNA (0.43) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | claimed |