Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110427 | 0.86 | ALOX5 (0.36) | ALOX5NFKB1NFKB2RELATHRA | |
| SCHEMBL17260612 | 0.85 | THRA (0.49) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL815527 | 0.85 | GABRA1 (0.44) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL816093 | 0.81 | ALOX5 (0.49) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL9971674 | 0.78 | CYP4F2 (0.49) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL17260589 | 0.77 | THRA (0.46) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL10015715 | 0.77 | ALOX5 (0.44) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL16182674 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL28002486 | 0.77 | ALDH1A1 (0.44) | GABRA1GABRB2ALOX5THRATHRB | |
| SCHEMBL28666259 | 0.76 | THRA (0.47) | GABRA1GABRB2ALOX5NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633877-B1 | NOVEL PHENOLIC-HYDRAZIDE COMPOUNDS AND POLYOLEFIN COMPOSITIONS STABILIZED THEREWITH | EASTMAN CHEM CO (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5319127-A | Metal deactivator and antioxidant; useful for coating copper wire | EASTMAN CHEMICAL COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5302744-A | Phenolic-hydrazide compounds and polyolefin compositions stabilized therewith | EASTMAN KODAK COMPANY (US) | 1994-04-12 | — | — | US | disclosed |