Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17260612 | 0.86 | THRA (0.49) | GABRA1GABRB2ALDH1A1ALOX5NFKB1 | |
| SCHEMBL8767270 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1ALOX5NFKB1 | |
| SCHEMBL816093 | 0.82 | ALOX5 (0.49) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL9973601 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL9971674 | 0.80 | CYP4F2 (0.49) | GABRA1GABRB2ALDH1A1ALOX5NFKB1 | |
| SCHEMBL10015715 | 0.79 | ALOX5 (0.44) | GABRA1GABRB2ALDH1A1ALOX5NFKB1 | |
| SCHEMBL17260589 | 0.79 | THRA (0.46) | GABRA1GABRB2ALDH1A1ALOX5NFKB1 | |
| SCHEMBL16182674 | 0.78 | GABRA1 (0.50) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL28666259 | 0.78 | THRA (0.47) | GABRA1GABRB2ALOX5NFKB1NFKB2 | |
| SCHEMBL17260608 | 0.77 | PYGL (0.48) | ALDH1A1ALOX5NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518302-B2 | Stabilization of organic materials | BASF SE (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20120088869-A1 | STABILIZATION OF ORGANIC MATERIALS | GERSTER MICHELE (CH) | 2012-04-12 | — | — | US | disclosed |
| US-20110054220-A1 | POLYETHER POLYOLS, POLYESTER POLYOLS AND POLYURETHANES OF LOW RESIDUAL ALDEHYDE CONTENT | GOH CHIN SIONG | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088869-A1 | STABILIZATION OF ORGANIC MATERIALS | LPO, AOX1, SOD1 | GABRA1 3552/4885GABRB2 4501/4885ALDH1A1 6/4885 |
| US-20110054220-A1 | POLYETHER POLYOLS, POLYESTER POLYOLS AND POLYURETHANES OF LOW RESIDUAL ALDEHYDE CONTENT | PUF60, GPX4, AOX1 | GABRA1 2457/4885GABRB2 1776/4885ALDH1A1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.