Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 9/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746321 | 0.79 | GAA (0.34) | GABRA2GABRB2GABRB3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6578636 | 0.76 | GAA (0.33) | GABRA2GABRB2GABRB3 | |
| SCHEMBL1768628 | 0.71 | PDE2A (0.40) | GABRA2GABRB2GABRB3ALDH1A1 | |
| SCHEMBL5713364 | 0.70 | GAA (0.45) | NPSR1ALDH1A1LMNA | |
| SCHEMBL26627748 | 0.68 | TSHR (0.55) | ALDH1A1LMNA | |
| SCHEMBL9725591 | 0.67 | PDE2A (0.40) | GABRA2GABRB2ALDH1A1 | |
| SCHEMBL241686 | 0.67 | ALDH1A1 (0.42) | GABRA2GABRB2GABRB3NPSR1ALDH1A1 | |
| SCHEMBL13487562 | 0.67 | GABRB3 (0.46) | GABRA2GABRB2GABRB3 | |
| SCHEMBL12864135 | 0.67 | GABRB3 (0.36) | GABRB3ALDH1A1LMNAPKM | |
| SCHEMBL16320650 | 0.67 | GABRA2 (0.38) | GABRA2GABRB2GABRB3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788484-A1 | 2-CHLORO-N- 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996012707-A1 | 2-CHLORO-N-[1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-02 | — | — | WO | disclosed |