Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767413 | 0.96 | PKM (0.37) | PKMLMNAHTTDRD3ADRA1D | |
| SCHEMBL8772395 | 0.82 | LMNA (0.39) | PKMLMNAHTTADRA1DADRA1A | |
| SCHEMBL8766787 | 0.82 | HTT (0.39) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL8766468 | 0.77 | PKM (0.41) | PKMLMNACHRM3NAAAHTT | |
| SCHEMBL8767339 | 0.74 | HTT (0.38) | PKMLMNAHTTADRA1DADRA1A | |
| SCHEMBL8767314 | 0.73 | PKM (0.38) | PKMLMNAHTTADRA1DADRA1A | |
| SCHEMBL8766792 | 0.71 | TRPA1 (0.40) | LMNANAAAMMP9MMP1MMP3 | |
| SCHEMBL8767549 | 0.70 | LMNA (0.39) | LMNAMMP2MMP3 | |
| SCHEMBL8766856 | 0.69 | HTT (0.39) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL8772394 | 0.69 | TRPA1 (0.40) | LMNANAAAMMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | claimed |