Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867488 | 0.87 | CYP4F2 (0.44) | THRATHRBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8867866 | 0.81 | MEN1 (0.47) | THRATHRBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8867193 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9ANPC1RECQLHRH3 | |
| SCHEMBL8867192 | 0.78 | THRA (0.65) | THRATHRBTGM2 | |
| SCHEMBL8767860 | 0.76 | RAD51 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1PLAU | |
| SCHEMBL12994621 | 0.76 | TGM2 (0.59) | SMN1; SMN2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL4153167 | 0.75 | TGM2 (0.57) | SMN1; SMN2RAB9ANPC1RECQLALDH1A1 | |
| SCHEMBL8867661 | 0.75 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1RECQLALDH1A1 | |
| SCHEMBL8867545 | 0.74 | NPC1 (0.59) | SMN1; SMN2RAB9ANPC1HRH3ALDH1A1 | |
| SCHEMBL8868161 | 0.74 | CNR1 (0.50) | THRATHRBSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |