Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768549 | 0.86 | HDAC3 (0.41) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8420680 | 0.79 | NR1H4 (0.39) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8767168 | 0.75 | L3MBTL1 (0.50) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8422576 | 0.73 | AKR1C2 (0.48) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8420287 | 0.72 | HTT (0.53) | LMNAKDM4EALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8422536 | 0.72 | HTT (0.46) | LMNAL3MBTL1SMN1; SMN2CA12CA1 | |
| SCHEMBL8418609 | 0.71 | CA12 (0.43) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8422462 | 0.71 | L3MBTL1 (0.45) | LMNAL3MBTL1SMN1; SMN2CA12CA1 | |
| SCHEMBL8418613 | 0.71 | ALDH1A1 (0.40) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8420641 | 0.70 | L3MBTL1 (0.47) | LMNAL3MBTL1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |