Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767991 | 0.86 | LMNA (0.42) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8418613 | 0.77 | ALDH1A1 (0.40) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8422576 | 0.71 | AKR1C2 (0.48) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8420680 | 0.71 | NR1H4 (0.39) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8767168 | 0.71 | L3MBTL1 (0.50) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8420287 | 0.70 | HTT (0.53) | LMNACA12CA1CA2CA4 | |
| SCHEMBL8422536 | 0.70 | HTT (0.46) | L3MBTL1LMNACA12CA1CA2 | |
| SCHEMBL8418609 | 0.69 | CA12 (0.43) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8422412 | 0.69 | MEN1 (0.48) | GPR88L3MBTL1LMNACA12CA1 | |
| SCHEMBL8422462 | 0.69 | L3MBTL1 (0.45) | L3MBTL1LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |