Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767453 | 0.91 | LMNA (0.42) | L3MBTL1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL8768279 | 0.91 | LMNA (0.42) | L3MBTL1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL8097853 | 0.89 | LMNA (0.49) | L3MBTL1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL8103050 | 0.89 | LMNA (0.44) | L3MBTL1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL8916898 | 0.87 | L3MBTL1 (0.52) | L3MBTL1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL8104049 | 0.87 | LMNA (0.39) | L3MBTL1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL8766943 | 0.85 | PTGS2 (0.48) | TSHRCYSLTR1TDP1 | |
| SCHEMBL8767162 | 0.82 | LMNA (0.40) | L3MBTL1LMNASMN1; SMN2HTTBLM | |
| SCHEMBL8767110 | 0.82 | LMNA (0.40) | LMNATSHRSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8097851 | 0.82 | LMNA (0.51) | L3MBTL1LMNATSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673931-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |