Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917593 | 0.90 | L3MBTL1 (0.43) | L3MBTL1LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8874675 | 0.90 | L3MBTL1 (0.43) | L3MBTL1LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8097851 | 0.89 | LMNA (0.51) | L3MBTL1LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8917011 | 0.89 | LMNA (0.48) | LMNAKMT2ATSHRALDH1A1BLM | |
| SCHEMBL8874939 | 0.88 | LMNA (0.44) | L3MBTL1LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8768360 | 0.87 | L3MBTL1 (0.50) | L3MBTL1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL8874783 | 0.87 | KMT2A (0.42) | L3MBTL1LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8915935 | 0.84 | PTGS2 (0.51) | TDP1 | |
| SCHEMBL8870465 | 0.83 | LMNA (0.52) | LMNAKMT2ATSHRALDH1A1MAPT | |
| SCHEMBL8097853 | 0.82 | LMNA (0.49) | L3MBTL1LMNAKMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | claimed |
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |