Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623805 | 0.80 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP17A1 | |
| SCHEMBL8940232 | 0.80 | NR3C1 (0.60) | NR3C1ARPGRNR3C2CYP17A1 | |
| SCHEMBL9623656 | 0.78 | NR3C1 (0.37) | NR3C1ARPGRNR3C2CYP17A1 | |
| SCHEMBL9623603 | 0.78 | ABCB11 (0.38) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9623691 | 0.76 | NR3C1 (0.39) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL9622893 | 0.75 | NR3C1 (0.41) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL10582213 | 0.75 | NR3C1 (0.41) | NR3C1ARPGRNR3C2CYP19A1 | |
| SCHEMBL8768647 | 0.75 | CYP19A1 (0.40) | NR3C1ARCYP17A1SRD5A2CYP19A1 | |
| SCHEMBL8769318 | 0.74 | CYP19A1 (0.40) | NR3C1ARCYP17A1SRD5A2CYP19A1 | |
| SCHEMBL9624281 | 0.74 | NR3C1 (0.43) | NR3C1ARPGRNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |
| JP-8169897-A | — | — | None | — | — | JP | disclosed |
| JP-H08169897-A | NOVEL PRODUCTION OF 16 BETA-METHYL-STEROID AND NOVEL INTERMEDIATE | ROUSSEL UCLAF | 1996-07-02 | — | — | JP | disclosed |